Oxidative stress occurs when there is an imbalance between free radicals (unstable molecules that can damage cells) and antioxidants (molecules that neutralise free radicals) in your body. Free radicals are produced naturally during metabolic processes but environmental factors like pollution, smoking and poor diet can increase their levels. Diminished antioxidant capacity and endogenous factors like high hormone load (stress and reproductive) can also contribute to oxidative stress.

Joint health is essential for mobility, flexibility, and overall physical well-being.

Key Components of Joint Structure

1. Bones:

Joints form where two bones meet. Bones provide structural support …

For biohackers focused on longevity, it’s all about targeting the underlying mechanisms of ageing. From mitochondrial health to reducing inflammation and clearing out senescent cells, supplement strategies can make a significant difference. Here’s a rundown of eight well-researched supplements that can help slow down the ageing process, each supported by scientific evidence. 

Weight loss plateaus are a natural part of the journey and can be an opportunity to tune into your body’s signals. Instead of obsessing over numbers or calorie restriction, taking a holistic approach that integrates nutrition, hormones, lifestyle and stress management can help you overcome the plateau and achieve lasting results without feeling depleted or discouraged.

Vitamin B9, commonly referred to as folate, comes in many forms, and choosing the right one can make a significant difference in how your body uses it. You’ve likely seen different names on food packaging or supplements, such as folic acid, folate, folinic acid, and 5-MTHF, but they’re not all created equal.

If you have been experiencing challenges with your mental health, whether it's low mood, poor concentration, memory lapses or lack of motivation, it may be worth examining your nutrient intake. Your brain relies on specific vitamins and minerals to function properly and deficiencies in these key nutrients can significantly impact your mental wellbeing. Optimising your nutrient levels is a foundational step toward supporting better cognitive health and emotional balance.

Perimenopause is often a topic that women avoid, partly because we live in a society that doesn’t always support or understand this phase of life and partly because there is a misconception that there is nothing we can do to make this shift more seamless - we have no choice but to buckle up and deal with the hormonal hand we are dealt. It can feel like a confusing, isolating and challenging time, from both a physical and mental perspective. But it doesn’t have to be this way… With the right knowledge, preparation and lifestyle adjustments, you can navigate this transition with more ease, confidence and vitality. If you take anything from this article, it’s that there is so much we can do as women to prepare our bodies and minds for these shifts, empowering us to embrace the changes with greater ease and resilience.

Vitamin D is a crucial nutrient that plays a vital role in maintaining overall health. It is unique because it acts like both a vitamin and a hormone in the body. Here are some key reasons why vitamin D is important:

• Bone Health: Vitamin D helps the body absorb calcium, which is essential for building and maintaining strong bones. Without sufficient vitamin D, bones can become thin and brittle.

• Immune Support: It enhances the pathogen-fighting effects of monocytes and macrophages—white blood cells that are important parts of your immune defence—and decreases inflammation.

• Mood Regulation: Adequate levels of vitamin D are associated with improved mood and mental health. Low levels have been linked to conditions like depression.

• Muscle Function: Vitamin D contributes to muscle strength, reducing the risk of falls and fractures, especially in older adults.

As cold and flu season approaches, many people look for natural ways to support their immune system. One option gaining attention is probiotics, the good bacteria that live in your gut and help keep your body healthy.

But can they really help you fight off seasonal illnesses?

Kinoko Gold AHCC is a natural supplement made primarily from shiitake mushroom extract which is fermented, filtered and dried to produce a powdered supplement.

AHCC stands for Active Hexose Correlated Compound. The active compound in AHCC is alpha-glucans, which is unique to AHCC and thought to be key to its immune supporting effects.

Managing cortisol effectively involves supporting your body and nervous system to deal with on-going stress or as they recover from chronic stress. Key areas include regulating blood sugar, restoring your circadian rhythm, and practices that calm the stress response. Here's a practical guide to help you lower cortisol naturally.

Fibre-maxxing is a growing nutrition trend focused on increasing your daily fibre intake often well above the minimum recommended amounts. Many people still fall short of even the minimum recommended fibre intake, so increased awareness around fibre intake is generally a good thing. However, extremes or sudden changes (like massive fibre increases overnight) can backfire, causing bloating, discomfort, constipation or even nutrient absorption issues.

Blood sugar balance refers to the regulation of glucose (sugar) levels in the bloodstream to keep them within a healthy range. Proper balance ensures that the body has a stable supply of energy while preventing the detrimental effects of too high or too low blood sugar levels, or fluctuations. Blood sugar dysregulation can impact concentration, moods, energy levels, sleep, metabolic health, cardiovascular health, weight management and more. It can also increase diabetes risk and exacerbate chronic conditions and hormonal imbalances.

The immune system is the body’s natural defense against infections, and its function can be influenced by many factors, including diet, genetics, and nutrient levels. While there is no single food or supplement that can provide a "magic boost" to the immune system, optimising nutrient intake is essential for supporting immune health. Nutrients like vitamins A, C, D, folate, iron, and zinc are key to maintaining strong immune responses, and genetic factors can influence how well your body absorbs and utilises these nutrients.

Inflammation is the body's natural defence mechanism against injury and infection, a process that typically promotes healing. However, when inflammation persists and becomes chronic, it can trigger a range of serious health issues, including autoimmune diseases, cardiovascular problems, and metabolic disorders. While factors such as diet, stress, and environmental toxins significantly influence inflammation levels, genetics also plays a crucial role in determining your susceptibility to inflammatory conditions. This article delves into twelve specific genetic variants linked to an increased risk of chronic inflammation, offering insights into your genetic predisposition and how to tailor health strategies to mitigate these risks effectively.

Neurodegenerative diseases like Alzheimer’s and Parkinson’s are marked by progressive cognitive and motor impairment, largely due to cellular damage and the accumulation of toxic proteins in the brain, particularly beta-amyloid (Aβ) plaques. These protein clumps are linked to oxidative stress, inflammation, and neuronal death. Research has increasingly focused on curcumin, a bioactive compound in turmeric, for its neuroprotective properties and potential to mitigate the progression of these diseases.

Collagen is a structural protein that makes up about 30% of the body's protein content. It is a key component  of connective tissues such as skin, cartilage, bones, tendons, and ligaments. Collagen provides structural  support and strength to various tissues and is essential for maintaining skin elasticity and firmness. 

Biohacking is the practice of using science, technology, and lifestyle interventions to optimise health, performance, and well-being. Often viewed as the art and science of "hacking" biology, biohacking combines principles from fields such as nutrition, neuroscience, genetics, and exercise physiology to help people improve their physical and mental health. Biohacking can be as simple as taking supplements to enhance cognitive performance or as complex as implanting devices to monitor physiological responses.

The distinction between methylated or active vitamins and their non-active counterparts is crucial for many individuals, especially those with specific genetic variations (SNPs) that impact vitamin metabolism. Here, we’ll explore these differences, highlight key examples, and explain how genetic SNP testing can play a significant role in determining which vitamins are best for you.